Following a decision in 2015 to exit the Clarecastle facility, final production was undertaken in November 2019 and pharmaceutical operations ceased in March 2020.
A planning application to decommission the site was submitted to Clare County Council in June 2020 and a formal final grant of planning permission to commence work on the phased demolition of all existing buildings, structures and infrastructure, on, in and under the site of the existing Roche pharmaceutical plant at Clarehill, Clarecastle, Co Clare was issued by Clare County Council on 3 February 2021. This work is now underway and will continue in phases through to mid 2029, when the groundwater validation monitoring phase is complete and the site's EPA licence is officially surrendered.